Does NMN slow human ageing? Updated October 2026: what human trials reveal about NAD⁺, metabolic outcomes, short-term safety, study funding and the cost of supplements.
My 25(OH)D rose only modestly while taking 5,000 IU/day, but that does not prove 10,000 IU/day is safe or beneficial. Current guidance sets a 4,000 IU/day adult upper intake level for unsupervised long-term use and does not support routine high-dose supplementation in healthy adults.
Fat-burner supplements rarely produce large weight-loss effects. This article separates stimulant effects, L-carnitine, workout ingredients and marketing claims from measured outcomes.
Cholesterol is essential to human biology, but apoB-containing particles, especially LDL, have a causal role in atherosclerosis. Dietary cholesterol is only one part of the picture, and lowering LDL reduces cardiovascular events and can produce modest plaque regression.
Fluoride toothpaste reduces tooth decay and is generally safe when used as directed. The main practical concern is repeated swallowing by young children, which can increase fluorosis risk. Claims that ordinary toothpaste routinely causes thyroid or melatonin problems are not established.
Does resveratrol slow aging or explain the French paradox? Human trials show some modest metabolic effects, but no evidence that resveratrol extends human lifespan.
In this brief article, I want to discuss the importance of timely and candid communication, and also…
Inspired by my earlier exploratory facial-age experiment, I analyzed images of David Sinclair from different years. The…
Can you trust your InBody or smart scale? A water experiment, an analysis of 1,924 adults and research on 15 devices explain what body-fat readings can and cannot tell you.
Molecular handedness matters in biology, but the leap from “chirality matters” to “processed food is dangerous because of mirror molecules” is not supported. The narrower hypothesis remains scientifically interesting.
Sadhguru’s nutrition framework contains ideas that overlap with modern evidence and others that remain traditional or speculative. Here is a point-by-point separation of evidence, plausible mechanisms, and open hypotheses.
TallyAge uses a peer-reviewed cheek-cell epigenetic clock, but does a younger score mean slower aging or longer life? Here is what CheekAge validation studies actually show.
An evidence audit of David Sinclair’s 2026 longevity routine: NMN, resveratrol, metformin, nattokinase, epigenetic reprogramming, clinical trials and what remains unproved.
TMD and tinnitus often occur together, but association does not prove the jaw caused the ringing. Learn when somatic tinnitus is plausible and whether treating TMD can help.
Voice can be trained, but the old version of this article mixed useful practice ideas with claims…
How to measure blood pressure accurately at home, choose a validated cuff, understand why U.S. and European thresholds differ, and know when a reading needs medical attention.
I compared apparent facial age estimates from video screenshots. The results are interesting, but they do not measure biological age or prove rejuvenation.
Does an anti-inflammatory diet slow ageing? Randomised trials show changes in some biomarkers and cardiovascular outcomes, but longer life remains unproven.
Wet cupping may provide short-term pain relief for some conditions, but evidence quality is generally low. It has not been shown to remove toxins, cholesterol or ‘bad blood’. This article separates my personal experience from clinical evidence and safety considerations.
Oral GABA has limited human evidence for stress and sleep, preliminary data for body composition, and small studies showing growth-hormone effects. My workout experience is anecdotal, not proof.